Spinocerebellar ataxia-8 (SCA8; {608768}) is a neurodegenerative disorder caused by a CTG/CAG trinucleotide repeat expansion on chromosome 13q21 (see {603680.0001} and {613289.0001}). Two genes span the CTG/CAG repeat and are expressed in opposite directions: ATXN8, which encodes a nearly pure polyglutamine expansion protein in the CAG direction, and ATXN8OS ({603680}), which, when transcribed, produces a noncoding CUG expansion RNA ({2:Moseley et al., 2006}).[supplied by OMIM, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATXN8-20-RE | 20 (40 μL) | 200 μL |  |
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| ATXN8-20-OR | 20 (40 μL) | 200 μL |  |
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| ATXN8-20-GO | 20 (40 μL) | 200 μL |  |
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| ATXN8-20-GR | 20 (40 μL) | 200 μL |  |
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| ATXN8-20-AQ | 20 (40 μL) | 200 μL |  |
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Spinocerebellar ataxia-8 (SCA8; {608768}) is a neurodegenerative disorder caused by a CTG/CAG trinucleotide repeat expansion on chromosome 13q21 (see {603680.0001} and {613289.0001}). Two genes span the CTG/CAG repeat and are expressed in opposite directions: ATXN8, which encodes a nearly pure polyglutamine expansion protein in the CAG direction, and ATXN8OS ({603680}), which, when transcribed, produces a noncoding CUG expansion RNA ({2:Moseley et al., 2006}).[supplied by OMIM, Mar 2010]
Gene Symbol : ATXN8
Gene Name : Ataxin 8
Chromosome : CHR 13: 0-0
Locus : 13q21
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