This gene is an antisense transcript to the KLHL1 gene (homolog to the Drosophila KELCH gene); it does not itself appear to be protein coding. A TAC/TGC trinucleotide repeat expansion that is incorporated into this gene transcript, but not the KLHL1 transcript, causes spinocerebellar ataxia type 8. Presumably the expansion interferes with normal antisense function of this transcript. [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATXN8OS-20-RE | 20 (40 μL) | 200 μL |  |
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| ATXN8OS-20-OR | 20 (40 μL) | 200 μL |  |
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| ATXN8OS-20-GO | 20 (40 μL) | 200 μL |  |
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| ATXN8OS-20-GR | 20 (40 μL) | 200 μL |  |
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| ATXN8OS-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is an antisense transcript to the KLHL1 gene (homolog to the Drosophila KELCH gene); it does not itself appear to be protein coding. A TAC/TGC trinucleotide repeat expansion that is incorporated into this gene transcript, but not the KLHL1 transcript, causes spinocerebellar ataxia type 8. Presumably the expansion interferes with normal antisense function of this transcript. [provided by RefSeq, Oct 2008]
Gene Symbol : ATXN8OS
Gene Name : ATXN8 opposite strand (non-protein coding)
Chromosome : CHR 13: 701,072,12-701,397,52
Locus : 13q21.33
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