This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AURKC-20-RE | 20 (40 μL) | 200 μL |  |
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| AURKC-20-OR | 20 (40 μL) | 200 μL |  |
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| AURKC-20-GO | 20 (40 μL) | 200 μL |  |
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| AURKC-20-GR | 20 (40 μL) | 200 μL |  |
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| AURKC-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Symbol : AURKC
Gene Name : Aurora kinase C
Chromosome : CHR 19: 572,303,16-572,355,49
Locus : 19q13.43
Alt. Genes : MPHOSPH9
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