The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
AXL-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
AXL-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
AXL-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
AXL-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
AXL-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Gene Symbol : AXL
Gene Name : AXL receptor tyrosine kinase
Chromosome : CHR 19: 412,191,98-412,617,66
Locus : 19q13.2
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