This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BABAM2-20-RE | 20 (40 μL) | 200 μL |  |
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| BABAM2-20-OR | 20 (40 μL) | 200 μL |  |
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| BABAM2-20-GO | 20 (40 μL) | 200 μL |  |
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| BABAM2-20-GR | 20 (40 μL) | 200 μL |  |
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| BABAM2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016]
Gene Symbol : BABAM2
Gene Name : BRISC and BRCA1 A complex member 2
Chromosome : CHR 2: 278,906,14-283,389,00
Locus : 2p23.2
Alt. Genes : FEM1B
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