This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BACE2-20-RE | 20 (40 μL) | 200 μL |  |
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| BACE2-20-OR | 20 (40 μL) | 200 μL |  |
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| BACE2-20-GO | 20 (40 μL) | 200 μL |  |
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| BACE2-20-GR | 20 (40 μL) | 200 μL |  |
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| BACE2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Symbol : BACE2
Gene Name : Beta-site APP-cleaving enzyme 2
Chromosome : CHR 21: 411,678,00-412,825,33
Locus : 21q22.2-q22.3
Alt. Genes : FEM1B
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