This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCL11B-20-RE | 20 (40 μL) | 200 μL |  |
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| BCL11B-20-OR | 20 (40 μL) | 200 μL |  |
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| BCL11B-20-GO | 20 (40 μL) | 200 μL |  |
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| BCL11B-20-GR | 20 (40 μL) | 200 μL |  |
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| BCL11B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Gene Symbol : BCL11B
Gene Name : B-cell CLL/lymphoma 11B
Chromosome : CHR 14: 992,717,12-991,692,86
Locus : 14q32.2
Alt. Genes : HIPK3
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