This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCL2L12-20-RE | 20 (40 μL) | 200 μL |  |
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| BCL2L12-20-OR | 20 (40 μL) | 200 μL |  |
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| BCL2L12-20-GO | 20 (40 μL) | 200 μL |  |
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| BCL2L12-20-GR | 20 (40 μL) | 200 μL |  |
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| BCL2L12-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Symbol : BCL2L12
Gene Name : BCL2 like 12
Chromosome : CHR 19: 496,650,71-496,739,15
Locus : 19q13.33
Alt. Genes : RASA4
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