This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCL3-20-RE | 20 (40 μL) | 200 μL |  |
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| BCL3-20-OR | 20 (40 μL) | 200 μL |  |
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| BCL3-20-GO | 20 (40 μL) | 200 μL |  |
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| BCL3-20-GR | 20 (40 μL) | 200 μL |  |
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| BCL3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]
Gene Symbol : BCL3
Gene Name : B-cell CLL/lymphoma 3
Chromosome : CHR 19: 447,426,20-447,600,43
Locus : 19q13.32
Alt. Genes : LINC01587
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