This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCLAF1-20-RE | 20 (40 μL) | 200 μL |  |
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| BCLAF1-20-OR | 20 (40 μL) | 200 μL |  |
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| BCLAF1-20-GO | 20 (40 μL) | 200 μL |  |
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| BCLAF1-20-GR | 20 (40 μL) | 200 μL |  |
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| BCLAF1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : BCLAF1
Gene Name : BCL2 associated transcription factor 1
Chromosome : CHR 6: 136,290,644-136,256,862
Locus : 6q23.3
Alt. Genes : ZNF263
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