This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BEX2-20-RE | 20 (40 μL) | 200 μL |  |
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| BEX2-20-OR | 20 (40 μL) | 200 μL |  |
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| BEX2-20-GO | 20 (40 μL) | 200 μL |  |
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| BEX2-20-GR | 20 (40 μL) | 200 μL |  |
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| BEX2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Symbol : BEX2
Gene Name : Brain expressed X-linked 2
Chromosome : CHR X: 103,311,045-103,309,345
Locus : Xq22.2
Alt. Genes : DPYSL4
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