This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BIRC3-20-RE | 20 (40 μL) | 200 μL |  |
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| BIRC3-20-OR | 20 (40 μL) | 200 μL |  |
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| BIRC3-20-GO | 20 (40 μL) | 200 μL |  |
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| BIRC3-20-GR | 20 (40 μL) | 200 μL |  |
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| BIRC3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
Gene Symbol : BIRC3
Gene Name : Baculoviral IAP repeat containing 3
Chromosome : CHR 11: 102,317,449-102,339,402
Locus : 11q22.2
Alt. Genes : CTDSPL
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