The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BLM-20-RE | 20 (40 μL) | 200 μL |  |
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| BLM-20-OR | 20 (40 μL) | 200 μL |  |
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| BLM-20-GO | 20 (40 μL) | 200 μL |  |
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| BLM-20-GR | 20 (40 μL) | 200 μL |  |
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| BLM-20-AQ | 20 (40 μL) | 200 μL |  |
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The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008]
Gene Symbol : BLM
Gene Name : Bloom syndrome RecQ like helicase
Chromosome : CHR 15: 907,173,26-908,154,61
Locus : 15q26.1
Alt. Genes : SGK2
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