The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BMF-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| BMF-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| BMF-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| BMF-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| BMF-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : BMF
Gene Name : Bcl2 modifying factor
Chromosome : CHR 15: 401,088,83-400,878,89
Locus : 15q15.1
Alt. Genes : TRAP1
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.