This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BMP10-20-RE | 20 (40 μL) | 200 μL |  |
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| BMP10-20-OR | 20 (40 μL) | 200 μL |  |
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| BMP10-20-GO | 20 (40 μL) | 200 μL |  |
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| BMP10-20-GR | 20 (40 μL) | 200 μL |  |
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| BMP10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]
Gene Symbol : BMP10
Gene Name : Bone morphogenetic protein 10
Chromosome : CHR 2: 688,715,16-688,654,80
Locus : 2p13.3
Alt. Genes : FEM1B
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