The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BRAT1-20-RE | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-OR | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-GO | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-GR | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
Gene Symbol : BRAT1
Gene Name : BRCA1 associated ATM activator 1
Chromosome : CHR 7: 255,575,7-253,780,9
Locus : 7p22.3
Alt. Genes : LRPPRC
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