The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BRD4-20-RE | 20 (40 μL) | 200 μL |  |
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| BRD4-20-OR | 20 (40 μL) | 200 μL |  |
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| BRD4-20-GO | 20 (40 μL) | 200 μL |  |
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| BRD4-20-GR | 20 (40 μL) | 200 μL |  |
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| BRD4-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : BRD4
Gene Name : Bromodomain containing 4
Chromosome : CHR 19: 153,325,42-152,368,35
Locus : 19p13.12
Alt. Genes : PLXNC1
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