This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BRINP3-20-RE | 20 (40 μL) | 200 μL |  |
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| BRINP3-20-OR | 20 (40 μL) | 200 μL |  |
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| BRINP3-20-GO | 20 (40 μL) | 200 μL |  |
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| BRINP3-20-GR | 20 (40 μL) | 200 μL |  |
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| BRINP3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Gene Symbol : BRINP3
Gene Name : BMP/retinoic acid inducible neural specific 3
Chromosome : CHR 1: 190,477,996-190,097,661
Locus : 1q31.1
Alt. Genes : OPTN
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