This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BRMS1-20-RE | 20 (40 μL) | 200 μL |  |
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| BRMS1-20-OR | 20 (40 μL) | 200 μL |  |
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| BRMS1-20-GO | 20 (40 μL) | 200 μL |  |
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| BRMS1-20-GR | 20 (40 μL) | 200 μL |  |
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| BRMS1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : BRMS1
Gene Name : Breast cancer metastasis suppressor 1
Chromosome : CHR 11: 663,451,10-663,373,32
Locus : 11q13.2
Alt. Genes : PLXNC1
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