The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BTN3A3-20-RE | 20 (40 μL) | 200 μL |  |
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| BTN3A3-20-OR | 20 (40 μL) | 200 μL |  |
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| BTN3A3-20-GO | 20 (40 μL) | 200 μL |  |
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| BTN3A3-20-GR | 20 (40 μL) | 200 μL |  |
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| BTN3A3-20-AQ | 20 (40 μL) | 200 μL |  |
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The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]
Gene Symbol : BTN3A3
Gene Name : Butyrophilin subfamily 3 member A3
Chromosome : CHR 6: 264,404,71-264,534,14
Locus : 6p22.2
Alt. Genes : RPP38
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