This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
C1ORF56-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
C1ORF56-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
C1ORF56-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
C1ORF56-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
C1ORF56-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]
Gene Symbol : C1ORF56
Gene Name : Chromosome 1 open reading frame 56
Chromosome : CHR 1: 151,047,782-151,051,419
Locus : 1q21.3
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