This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C4BPA-20-RE | 20 (40 μL) | 200 μL |  |
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| C4BPA-20-OR | 20 (40 μL) | 200 μL |  |
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| C4BPA-20-GO | 20 (40 μL) | 200 μL |  |
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| C4BPA-20-GR | 20 (40 μL) | 200 μL |  |
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| C4BPA-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]
Gene Symbol : C4BPA
Gene Name : Complement component 4 binding protein alpha
Chromosome : CHR 1: 207,104,231-207,144,971
Locus : 1q32.2
Alt. Genes : HCG9
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