This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C5AR2-20-RE | 20 (40 μL) | 200 μL |  |
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| C5AR2-20-OR | 20 (40 μL) | 200 μL |  |
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| C5AR2-20-GO | 20 (40 μL) | 200 μL |  |
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| C5AR2-20-GR | 20 (40 μL) | 200 μL |  |
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| C5AR2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Symbol : C5AR2
Gene Name : Complement component 5a receptor 2
Chromosome : CHR 19: 473,316,13-473,420,79
Locus : 19q13.32
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