C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C8A-20-RE | 20 (40 μL) | 200 μL |  |
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| C8A-20-OR | 20 (40 μL) | 200 μL |  |
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| C8A-20-GO | 20 (40 μL) | 200 μL |  |
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| C8A-20-GR | 20 (40 μL) | 200 μL |  |
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| C8A-20-AQ | 20 (40 μL) | 200 μL |  |
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C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008]
Gene Symbol : C8A
Gene Name : Complement C8 alpha chain
Chromosome : CHR 1: 568,547,69-569,182,20
Locus : 1p32.2
Alt. Genes : SGK2
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