Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CA12-20-RE | 20 (40 μL) | 200 μL |  |
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| CA12-20-OR | 20 (40 μL) | 200 μL |  |
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| CA12-20-GO | 20 (40 μL) | 200 μL |  |
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| CA12-20-GR | 20 (40 μL) | 200 μL |  |
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| CA12-20-AQ | 20 (40 μL) | 200 μL |  |
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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014]
Gene Symbol : CA12
Gene Name : Carbonic anhydrase 12
Chromosome : CHR 15: 633,821,65-633,213,77
Locus : 15q22.2
Alt. Genes : PREB
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