Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CABIN1-20-RE | 20 (40 μL) | 200 μL |  |
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| CABIN1-20-OR | 20 (40 μL) | 200 μL |  |
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| CABIN1-20-GO | 20 (40 μL) | 200 μL |  |
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| CABIN1-20-GR | 20 (40 μL) | 200 μL |  |
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| CABIN1-20-AQ | 20 (40 μL) | 200 μL |  |
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Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]
Gene Symbol : CABIN1
Gene Name : Calcineurin binding protein 1
Chromosome : CHR 22: 240,111,91-241,786,27
Locus : 22q11.23
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