The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CACNA1B-20-RE | 20 (40 μL) | 200 μL |  |
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| CACNA1B-20-OR | 20 (40 μL) | 200 μL |  |
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| CACNA1B-20-GO | 20 (40 μL) | 200 μL |  |
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| CACNA1B-20-GR | 20 (40 μL) | 200 μL |  |
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| CACNA1B-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Symbol : CACNA1B
Gene Name : Calcium voltage-gated channel subunit alpha1 B
Chromosome : CHR 9: 137,877,788-138,124,623
Locus : 9q34.3
Alt. Genes : OPTN
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