This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CACNA2D4-20-RE | 20 (40 μL) | 200 μL |  |
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| CACNA2D4-20-OR | 20 (40 μL) | 200 μL |  |
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| CACNA2D4-20-GO | 20 (40 μL) | 200 μL |  |
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| CACNA2D4-20-GR | 20 (40 μL) | 200 μL |  |
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| CACNA2D4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : CACNA2D4
Gene Name : Calcium voltage-gated channel auxiliary subunit alpha2delta 4
Chromosome : CHR 12: 192,260,5-179,195,6
Locus : 12p13.33
Alt. Genes : RBM12
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