The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CARD10-20-RE | 20 (40 μL) | 200 μL |  |
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| CARD10-20-OR | 20 (40 μL) | 200 μL |  |
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| CARD10-20-GO | 20 (40 μL) | 200 μL |  |
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| CARD10-20-GR | 20 (40 μL) | 200 μL |  |
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| CARD10-20-AQ | 20 (40 μL) | 200 μL |  |
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The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]
Gene Symbol : CARD10
Gene Name : Caspase recruitment domain family member 10
Chromosome : CHR 22: 375,192,02-374,903,61
Locus : 22q13.1
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