The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CASC3-20-RE | 20 (40 μL) | 200 μL |  |
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| CASC3-20-OR | 20 (40 μL) | 200 μL |  |
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| CASC3-20-GO | 20 (40 μL) | 200 μL |  |
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| CASC3-20-GR | 20 (40 μL) | 200 μL |  |
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| CASC3-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]
Gene Symbol : CASC3
Gene Name : Cancer susceptibility 3
Chromosome : CHR 17: 401,402,53-401,721,77
Locus : 17q21.1
Alt. Genes : LRPPRC
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