The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CASR-20-RE | 20 (40 μL) | 200 μL |  |
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| CASR-20-OR | 20 (40 μL) | 200 μL |  |
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| CASR-20-GO | 20 (40 μL) | 200 μL |  |
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| CASR-20-GR | 20 (40 μL) | 200 μL |  |
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| CASR-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
Gene Symbol : CASR
Gene Name : Calcium sensing receptor
Chromosome : CHR 3: 122,183,682-122,286,502
Locus : 3q13.33-q21.1
Alt. Genes : HIPK3
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