This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CBLL1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
CBLL1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
CBLL1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
CBLL1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
CBLL1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]
Gene Symbol : CBLL1
Gene Name : Cbl proto-oncogene like 1
Chromosome : CHR 7: 107,743,496-107,764,996
Locus : 7q22.3
Alt. Genes : ZNF263
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