This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCL11-20-RE | 20 (40 μL) | 200 μL |  |
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| CCL11-20-OR | 20 (40 μL) | 200 μL |  |
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| CCL11-20-GO | 20 (40 μL) | 200 μL |  |
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| CCL11-20-GR | 20 (40 μL) | 200 μL |  |
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| CCL11-20-AQ | 20 (40 μL) | 200 μL |  |
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This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Gene Symbol : CCL11
Gene Name : C-C motif chemokine ligand 11
Chromosome : CHR 17: 342,856,67-342,881,79
Locus : 17q12
Alt. Genes : TM9SF1
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