The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCNG2-20-RE | 20 (40 μL) | 200 μL |  |
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| CCNG2-20-OR | 20 (40 μL) | 200 μL |  |
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| CCNG2-20-GO | 20 (40 μL) | 200 μL |  |
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| CCNG2-20-GR | 20 (40 μL) | 200 μL |  |
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| CCNG2-20-AQ | 20 (40 μL) | 200 μL |  |
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The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]
Gene Symbol : CCNG2
Gene Name : Cyclin G2
Chromosome : CHR 4: 771,572,03-771,700,59
Locus : 4q21.1
Alt. Genes : LRPPRC
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