The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCR2-20-RE | 20 (40 μL) | 200 μL |  |
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| CCR2-20-OR | 20 (40 μL) | 200 μL |  |
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| CCR2-20-GO | 20 (40 μL) | 200 μL |  |
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| CCR2-20-GR | 20 (40 μL) | 200 μL |  |
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| CCR2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
Gene Symbol : CCR2
Gene Name : C-C motif chemokine receptor 2
Chromosome : CHR 3: 463,537,43-463,609,39
Locus : 3p21.31
Alt. Genes : STAG1
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