This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCR6-20-RE | 20 (40 μL) | 200 μL |  |
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| CCR6-20-OR | 20 (40 μL) | 200 μL |  |
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| CCR6-20-GO | 20 (40 μL) | 200 μL |  |
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| CCR6-20-GR | 20 (40 μL) | 200 μL |  |
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| CCR6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : CCR6
Gene Name : C-C motif chemokine receptor 6
Chromosome : CHR 6: 167,111,806-167,139,140
Locus : 6q27
Alt. Genes : RAD50
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