The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCT4-20-RE | 20 (40 μL) | 200 μL |  |
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| CCT4-20-OR | 20 (40 μL) | 200 μL |  |
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| CCT4-20-GO | 20 (40 μL) | 200 μL |  |
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| CCT4-20-GR | 20 (40 μL) | 200 μL |  |
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| CCT4-20-AQ | 20 (40 μL) | 200 μL |  |
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The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]
Gene Symbol : CCT4
Gene Name : Chaperonin containing TCP1 subunit 4
Chromosome : CHR 2: 618,886,70-618,681,26
Locus : 2p15
Alt. Genes : ENAM
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