The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CD276-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
CD276-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
CD276-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
CD276-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
CD276-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Symbol : CD276
Gene Name : CD276 molecule
Chromosome : CHR 15: 736,839,65-737,145,17
Locus : 15q24.1
Alt. Genes : FEM1B
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