The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CD63-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
CD63-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
CD63-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
CD63-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
CD63-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Gene Symbol : CD63
Gene Name : CD63 molecule
Chromosome : CHR 12: 557,296,72-557,254,42
Locus : 12q13.2
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