This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD82-20-RE | 20 (40 μL) | 200 μL |  |
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| CD82-20-OR | 20 (40 μL) | 200 μL |  |
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| CD82-20-GO | 20 (40 μL) | 200 μL |  |
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| CD82-20-GR | 20 (40 μL) | 200 μL |  |
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| CD82-20-AQ | 20 (40 μL) | 200 μL |  |
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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : CD82
Gene Name : CD82 molecule
Chromosome : CHR 11: 445,655,90-446,203,62
Locus : 11p11.2
Alt. Genes : FEM1B
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