This gene represents a retrogene of cell division cycle 14B (CDC14B), which is located on chromosome 9. The introns in the coding sequence have been processed out relative to the CDC14B locus, but there is an intact open reading frame that is missing only some sequence at the N-terminus, including the nuclear localiztion signal, relative to proteins encoded by the CDC14B gene. There is a difference in the subcellular localization of the protein encoded by this gene, relative to its parental gene product. While the parental gene product displays microtubular localization, GFP chimeras of the protein encoded by this gene localize to the endoplasmic reticulum, indicating a possible new functional role for this gene. [provided by RefSeq, Nov 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CDC14C-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
CDC14C-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
CDC14C-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
CDC14C-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
CDC14C-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene represents a retrogene of cell division cycle 14B (CDC14B), which is located on chromosome 9. The introns in the coding sequence have been processed out relative to the CDC14B locus, but there is an intact open reading frame that is missing only some sequence at the N-terminus, including the nuclear localiztion signal, relative to proteins encoded by the CDC14B gene. There is a difference in the subcellular localization of the protein encoded by this gene, relative to its parental gene product. While the parental gene product displays microtubular localization, GFP chimeras of the protein encoded by this gene localize to the endoplasmic reticulum, indicating a possible new functional role for this gene. [provided by RefSeq, Nov 2017]
Gene Symbol : CDC14C
Gene Name : Cell division cycle 14C, pseudogene
Chromosome : CHR 7: 489,245,60-489,274,52
Locus : 7p12.3
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