The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDC23-20-RE | 20 (40 μL) | 200 μL |  |
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| CDC23-20-OR | 20 (40 μL) | 200 μL |  |
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| CDC23-20-GO | 20 (40 μL) | 200 μL |  |
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| CDC23-20-GR | 20 (40 μL) | 200 μL |  |
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| CDC23-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]
Gene Symbol : CDC23
Gene Name : Cell division cycle 23
Chromosome : CHR 5: 138,213,342-138,187,647
Locus : 5q31.2
Alt. Genes : FEM1B
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