The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDC42BPA-20-RE | 20 (40 μL) | 200 μL |  |
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| CDC42BPA-20-OR | 20 (40 μL) | 200 μL |  |
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| CDC42BPA-20-GO | 20 (40 μL) | 200 μL |  |
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| CDC42BPA-20-GR | 20 (40 μL) | 200 μL |  |
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| CDC42BPA-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008]
Gene Symbol : CDC42BPA
Gene Name : CDC42 binding protein kinase alpha
Chromosome : CHR 1: 227,318,491-226,989,864
Locus : 1q42.13
Alt. Genes : PREB
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