Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDC42EP5-20-RE | 20 (40 μL) | 200 μL |  |
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| CDC42EP5-20-OR | 20 (40 μL) | 200 μL |  |
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| CDC42EP5-20-GO | 20 (40 μL) | 200 μL |  |
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| CDC42EP5-20-GR | 20 (40 μL) | 200 μL |  |
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| CDC42EP5-20-AQ | 20 (40 μL) | 200 μL |  |
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Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]
Gene Symbol : CDC42EP5
Gene Name : CDC42 effector protein 5
Chromosome : CHR 19: 544,732,89-544,650,24
Locus : 19q13.42
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