This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CDC73-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
CDC73-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
CDC73-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
CDC73-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
CDC73-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]
Gene Symbol : CDC73
Gene Name : Cell division cycle 73
Chromosome : CHR 1: 193,121,957-193,254,814
Locus : 1q31.2
Alt. Genes : LRPPRC
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