This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDCA4-20-RE | 20 (40 μL) | 200 μL |  |
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| CDCA4-20-OR | 20 (40 μL) | 200 μL |  |
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| CDCA4-20-GO | 20 (40 μL) | 200 μL |  |
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| CDCA4-20-GR | 20 (40 μL) | 200 μL |  |
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| CDCA4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]
Gene Symbol : CDCA4
Gene Name : Cell division cycle associated 4
Chromosome : CHR 14: 105,021,087-105,009,572
Locus : 14q32.33
Alt. Genes : CLEC3A
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