This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDH11-20-RE | 20 (40 μL) | 200 μL |  |
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| CDH11-20-OR | 20 (40 μL) | 200 μL |  |
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| CDH11-20-GO | 20 (40 μL) | 200 μL |  |
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| CDH11-20-GR | 20 (40 μL) | 200 μL |  |
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| CDH11-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Gene Symbol : CDH11
Gene Name : Cadherin 11
Chromosome : CHR 16: 651,261,11-649,437,52
Locus : 16q21
Alt. Genes : ZNF263
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