This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDH20-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CDH20-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CDH20-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CDH20-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| CDH20-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]
Gene Symbol : CDH20
Gene Name : Cadherin 20
Chromosome : CHR 18: 613,335,81-615,557,72
Locus : 18q21.33
Alt. Genes : KIF20A
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.