This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDH23-20-RE | 20 (40 μL) | 200 μL |  |
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| CDH23-20-OR | 20 (40 μL) | 200 μL |  |
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| CDH23-20-GO | 20 (40 μL) | 200 μL |  |
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| CDH23-20-GR | 20 (40 μL) | 200 μL |  |
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| CDH23-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]
Gene Symbol : CDH23
Gene Name : Cadherin related 23
Chromosome : CHR 10: 713,969,33-718,159,46
Locus : 10q22.1
Alt. Genes : ABI2
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