This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDK11B-20-RE | 20 (40 μL) | 200 μL |  |
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| CDK11B-20-OR | 20 (40 μL) | 200 μL |  |
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| CDK11B-20-GO | 20 (40 μL) | 200 μL |  |
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| CDK11B-20-GR | 20 (40 μL) | 200 μL |  |
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| CDK11B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Symbol : CDK11B
Gene Name : Cyclin dependent kinase 11B
Chromosome : CHR 1: 165,983,8-163,522,5
Locus : 1p36.33
Alt. Genes : PNRC1
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